Urticaria Test (Histamine Releasing)

£198.95

Histamine is a substance that is released from specialised cells called mast cells when they are activated, often as part of an allergic immune response. This test can help to diagnose a subgroup of chronic urticaria related to circulating histamine releasing auto antibodies.

Identifying this subgroup of patients has practical implications for their treatment.

Other tests for Chronic Urticaria:(Full blood count, liver and thyroid function, autoimmune antibodies, total specific IgE and some others)
Occasionally screening for allergens (food and airborne) are used if doctor suspects it to be of allergic nature.

Est. Result Turnaround Time : 10-14 days

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Urticaria is characterised by weals (hives) or angioedema (swellings, in 10%) or both (in 40%). There are several types of urticaria. Acute urticarial are when your symptom duration is less than 6 weeks and chronic urticara is when your symptoms are present for longer than 6 weeks with daily episodic weals.

A weal (or wheal) is a superficial skin-coloured or pale skin swelling, usually surrounded by erythema (redness) that lasts anything from a few minutes to 24 hours. Usually very itchy, it may have a burning sensation. Hives are often itchy and can be caused by a reaction to things like food, pollen, insect bites or chemicals. You can usually treat hives with antihistamines from a pharmacy. If it does not get better, a GP may prescribe steroids or stronger antihistamines.

Angioedema is deeper swelling within the skin or mucous membranes and can be skin-coloured or red. It resolves within 72 hours. Angioedema may be itchy or painful but is often asymptomatic. Angioedema may progress to a serious allergic reaction called anaphylaxis, so it is very important to seek medical advice if you develop angioedema.

Additional information

Est Result Turnaround Time

10-14 days